NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae

Researchers are developing a promising alternative to antibiotic treatment for infections caused by Klebsiella pneumoniae bacteria resistant to carbapenem antibiotics. The approach uses antibodies to target the K. pneumoniae protective capsule polysaccharide, allowing immune system cells called neutrophils to attack and kill the bacteria. The early stage, in vitro research was conducted by scientists at NIAID’s Rocky Mountain Laboratories and the New Jersey Medical School-Rutgers University.

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